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Water

About 60% of an adult’s body weight. Water is the most abundant substance in the body and the medium in which nearly all of life’s chemistry takes place.

  • Intracellular fluid — roughly two-thirds of body water, held inside cells.
  • Extracellular fluid — the remaining third: blood plasma, interstitial fluid (between cells), and small specialized pools such as cerebrospinal fluid and joint fluid.
  • Solvent — dissolves salts, sugars, and many other molecules so they can react and be transported.
  • Transport — the basis of blood and lymph.
  • Temperature control — absorbs heat with little change in temperature; evaporating sweat sheds heat.
  • Chemical participant — directly involved in reactions, especially the splitting of molecules (hydrolysis).
  • Cushioning and lubrication — protects the brain, joints, and a developing fetus.

Water’s ability to dissolve charged and polar substances is the single property that makes it the foundation of biological chemistry.