Skip to content

Epidermis

The thin, tough outer layer of the skin — the body’s true surface.

The skin and its appendages A cross-section of skin showing its three layers — epidermis, dermis and hypodermis — together with the hair, sebaceous glands and sweat glands that pass through them. A small inset shows a fingertip with its nail. Each label links to the article for that part. Nails Epidermis Hair Sebaceous glands Dermis Sweat glands Hypodermis Cross-section of skin and its appendages — schematic, not to scale.

Stacked layers of epithelial cells. New cells form at the base and are pushed upward, flattening and filling with the protein keratin as they go, until the dead outer cells are shed. Thick skin (palms, soles) has five named layers; thin skin has four.

  • Keratinocytes — the bulk of the layer; make keratin.
  • Melanocytes — make melanin, the pigment that colors skin and absorbs UV.
  • Langerhans cells — immune sentinels.
  • Merkel cells — involved in touch sensing.
  • Barrier and waterproofing — the outer dead layer seals the body.
  • UV protection — melanin shields deeper tissue.
  • Renewal — fully replaces itself roughly every month.

The visible skin surface is entirely dead cells; the living epidermis works underneath, constantly replacing what wears away.