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Fluid and Electrolyte Balance

The regulation of the body’s water and of the dissolved salts (electrolytes — chiefly sodium, potassium, and chloride) within it. Together these set the volume and the concentration of every body fluid.

  • Volume — the total amount of body water, which influences blood pressure.
  • Concentration (osmolarity) — how dilute or concentrated the fluids are, which must stay steady or cells will swell or shrink.
  • The kidneys are the main effector, fine-tuning how much water and salt are kept or excreted.
  • Vasopressin (ADH) controls water reabsorption.
  • Aldosterone, via the RAAS, controls sodium retention.
  • Thirst, triggered by the hypothalamus, drives water intake.

The body regulates water and salt together because each determines the other’s effect — it is balancing not just how much fluid there is, but how concentrated it is.