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Circadian Rhythm

The body’s internal, roughly-24-hour clock — the regulatory system that times daily cycles of sleep, alertness, hormone release, body temperature, and metabolism.

A small region of the hypothalamus (the suprachiasmatic nucleus) is the body’s master clock. It runs on its own near-24-hour cycle and is reset each day by light reaching the eyes — keeping it synchronized with the actual day.

The master clock signals the rest of the body partly through melatonin, released by the pineal gland in darkness. Most organs also keep their own local clocks, all kept in step with the master.

Jet lag and shift work pull the internal clock out of step with the environment, degrading sleep, mood, and metabolic health.

Circadian rhythm is regulation in the dimension of time — the body anticipates the coming day rather than merely reacting to it.